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首页> 外文期刊>International journal of antimicrobial agents >Antimicrobial resistance of Staphylococcus aureus isolated from skin infections
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Antimicrobial resistance of Staphylococcus aureus isolated from skin infections

机译：从皮肤感染中分离出的金黄色葡萄球菌的耐药性

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摘要

The antimicrobial susceptibility of 229 strains of Staphylococcus attreus isolated from various skin infections was determined against 22 antimicrobial agents by the agar dilution method. The clinical isolates were most sensitive to vancomycin, teicoplanin, mupirocin and fusidic acid. No strains were resistant to vancomycin or teicoplanin. Three strains were highly resistant (MIC greater than or equal to 100 mg/l) to mupirocin and eight strains to fusidic acid. The MIC50 of all antimicrobials, except for gentamicin, were below 3.13 mg/l. The incidence of resistance to penicillin, cephalosporins and clindamycin ranged from 20 to 30%. The occurrence of gentamicin, erythromycin and roxithromycin resistance was high at 55.2, 39.6 and 39.1%, respectively. Methicillin resistance occurred in 21.0% of strains. The incidence of organisms with MIC greater than or equal to 3.13 mg/l to oxacillin was 24.3%. These results were comparable to the average rate of MRSA in Japanese dermatological specimens. (C) 2002 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved. [References: 12]
机译：通过琼脂稀释法确定了从各种皮肤感染中分离出来的229株葡萄球菌的抗菌药对22种抗菌药的敏感性。临床分离株对万古霉素，替考拉宁，莫匹罗星和夫西地酸最敏感。没有菌株对万古霉素或替考拉宁有抗性。 3株对莫匹罗星具有高度抗性（MIC大于或等于100 mg / l），8株对夫西地酸具有抗性。除庆大霉素外，所有抗菌药物的MIC50均低于3.13 mg / l。对青霉素，头孢菌素和克林霉素的耐药率在20％至30％之间。庆大霉素，红霉素和罗红霉素的耐药率分别高达55.2％，39.6％和39.1％。 21.0％的菌株对甲氧西林产生抗药性。 MIC大于或等于3.13 mg / l的微生物对奥沙西林的发生率为24.3％。这些结果与日本皮肤病标本中MRSA的平均比率相当。 （C）2002 Elsevier Science B.V.和国际化学疗法学会。版权所有。 [参考：12]

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