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首页> 外文期刊>Key engineering materials >Ultrasonic Backscatter Response to Blood Flow Disturbance by a Severe Eccentric Stenosis
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Ultrasonic Backscatter Response to Blood Flow Disturbance by a Severe Eccentric Stenosis

机译：Ultrasonic Backscatter Response to Blood Flow Disturbance by a Severe Eccentric Stenosis

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Blood flow disturbance by a severe eccentric stenosis (～ 70 ) was investigated in a polystyrene tube (9.5 mm of inner diameter) of a mock flow loop. A modified Aloka 280 system with a 7.5 MHz linear array transducer was used to collect the RF (radio frequency) and video signals of B-mode images. Pulsatile flow was generated and controlled to observe the 'black hole (BH)' phenomenon, a hypo-echoic zone at the center stream, upstream of the stenosis. The BH from porcine whole blood was disturbed on the stenotic site but reappeared further downstream at 20 beats/min (bpm). At higher stroke rates (40 and 60 bpm), the BH was not observed downstream but a hyper-echoic parabolic profile appeared at each systole showing the periodic spatial variation further downstream up to 10 diameters. These bright profiles seemed to be due to enhancement of rouleaux formation by flow acceleration. The ultrasonic power from RBC suspensions under steady flow showed a strong echoic horizontal line downstream of a stenosis and its position and strength varied with flow speed. It seemed to be related with the boundary between the two disturbed flow zones. In conclusion, a severe eccentric stenosis disturbed the blood flow and red cell structures, so that the backscatter from porcine whole blood varied with flow speed, stroke rate, and position along the flow direction. Ultrasonic B-mode imaging may be a useful tool to visualize the blood flow and to study hemodynamics.

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