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>Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues
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Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues
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机译:Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues
The amyloid precursor protein (APP) is a type I transmembrane glycopro-tein widely studied for its role as the source of P-amyloid peptide, accumulation of which is causal in at least some cases of Alzheimer's disease (AD). APP is expressed ubiquitously and is involved in diverse biological processes.
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