Summary:IgA nephropathy, formerly known as Berger's Disease, is now recognized as the world's most common primary nephropathy. the rate of progression has recently been shown to be the same in childhood as well as adulthood (i.e. slightly more than 1/4 of the patients had end‐stage renal disease at follow up of 20 years). the pathogenesis may be associated with free‐radical release as demonstrated in experimental IgA nephropathy and indirectly in leucocytes of these patients. the use of vitamin E and fish oil is discus
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