机译:Anti-CTLA-4 therapy requires an Fc domain for efficacy
Dana Farber Canc Inst, Dept Canc Immunol & Virol, Boston, MA 02215 USA;
Childrens Hosp Boston, Program Cellular & Mol Med, Boston, MA 02115 USA;
Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USAMassachusetts Gen Hosp, Div Gastroenterol, Boston, MA 02114 USAMassachusetts Gen Hosp, Ctr Syst Biol, Boston, MA 02114 USA;
immunotherapy; CTLA-4; single-domain antibody; cancer; checkpoint blockade;