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>In Vivo Performance and Structural Relaxation of Biodegradable Bone Implants Made from Mg-Zn-Ca Bulk Metallic Glasses
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In Vivo Performance and Structural Relaxation of Biodegradable Bone Implants Made from Mg-Zn-Ca Bulk Metallic Glasses
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机译：In Vivo Performance and Structural Relaxation of Biodegradable Bone Implants Made from Mg-Zn-Ca Bulk Metallic Glasses
A study of Mg-based bulk metallic glasses (BMGs) as biodegradable bone implants is presented. The implantation site can affect performance, so the BMGs were evaluated in vivo in rat femurs using μ-CT scans at various times for more than 90 days. Estimates of H_2 evolution correlate well with previous in vitro studies and bone-implant contact is similar to that for Ti pins. One potential drawback of Mg-based BMGs in this application is embrittlement due to structural relaxation. Here, relaxation at 20 and 37℃ is examined, and an increase in the characteristic relaxation time, from 10 to 30 days at 20℃, is observed as Zn increases from 29 to 32 at., correlating with dramatically reduced hydrogen evolution.
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