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机译:社论

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摘要

With the advent of nanotechnology, the prospective use of engineered nanomaterials, defined as materials with a diameter below 100 nm, in many applications, due to their advantageous properties, has progressed rapidly. Over the last decade however, there has been increased debate regarding the potential harmful effects of nanomaterials. Predominantly, heightened concern has been expressed regarding the (potential) adverse health effects of nanoparticles (NPs). A plethora of both lab-based and epidemiological studies have previously indicated that inhalation of combustion derived NPs can cause adverse health effects, as well as augment pre-existing diseases, such as chronic obstructive pulmonary disease. Although there are obvious differences between combustion-derived NPs; which are polydispersed and have a chemically complex nature; and engineered NPs; which are in contrast monodispersed with precise chemically engineered characteristics; the same toxicological principles are assumed.
机译:随着纳米技术的出现,工程纳米材料被定义为直径小于100 nm的材料,由于其优越的性能,在许多应用中的前瞻性应用已迅速发展。然而,在过去的十年中,关于纳米材料的潜在有害影响的辩论越来越多。主要地,人们已经对纳米颗粒(NPs)的(潜在的)不良健康影响表示了高度关注。大量的基于实验室和流行病学的研究以前都表明,吸入燃烧衍生的NPs可能对健康造成不利影响,并加剧诸如慢​​性阻塞性肺疾病之类的既往疾病。尽管燃烧衍生的NP之间存在明显的差异;它们是多分散的并且具有化学复杂的性质;和工程化的NP;相反,它们是单分散的,具有精确的化学工程特性;假定相同的毒理学原理。

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