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首页> 外文期刊>International journal of colorectal disease. >Does bariatric surgery change olfactory perception? Results of the early postoperative course
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Does bariatric surgery change olfactory perception? Results of the early postoperative course

机译：减肥手术是否会改变嗅觉？术后早期过程的结果

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Purpose: Changes of food preference toward foods with low caloric density have been demonstrated after bariatric surgery and may contribute to sustained body weight loss. It has been hypothesized that olfactory perception as an integral part of food selection might be altered after bariatric surgery. Methods: Sniffin' Sticks? were used to investigate the olfactory perception of morbidly obese patients undergoing either Roux-en-Y gastric bypass (RYGB, n = 15) or sleeve gastrectomy (SG, n = 15) before 1, 6, 12, and 24 weeks after surgery. Obese patients without surgical intervention served as controls (CG, n = 12). Results are presented using the testing odor threshold, discrimination, and identification score (TDI; higher scores indicate better olfactory perception). Body weight loss was recorded. Results: Initial BMI of the SG group (56.04 ± 7.096 kg m-2) was higher compared to the BMI of the RYGB (48.71 ± 6.49 kg m-2) and CG (50.35 ± 6.78 kg m-2); p = 0.011. Body weight loss among the surgical groups was not different (p = 0.011) while controls did not lose weight. Mean baseline TDI scores were significantly lower in the SG group 27.1 ± 3.9 vs. 32.6 ± 3.6 (RYGB) and 32.1 ± 5.3 (CG), respectively, whereas there were after 24 weeks no changes in RYGB and CG patients; the TDI score in the SG group increased significantly to 31.1 ± 3.5 (p 0.01). Conclusions: Our data suggest that a substantial body weight loss per se does not affect olfactory perception. However, our results point towards improved olfactory perception after sleeve gastrectomy but not Roux-en-Y gastric bypass.
机译：目的：减肥手术后已证明食物偏爱低热量食物，这可能有助于持续减轻体重。据推测，减肥手术后嗅觉作为食物选择不可或缺的一部分可能会改变。方法：嗅探棒？被用于调查在手术后1、6、12和24周接受Roux-en-Y胃搭桥术（RYGB，n = 15）或袖式胃切除术（SG，n = 15）的病态肥胖患者的嗅觉。没有手术干预的肥胖患者作为对照（CG，n = 12）。使用测试的气味阈值，辨别力和识别分数（TDI;较高的分数表示更好的嗅觉）呈现结果。记录体重减轻。结果：SG组的初始BMI（56.04±7.096 kg m-2）高于RYGB（48.71±6.49 kg m-2）和CG的BMI（50.35±6.78 kg m-2）; p ＝ 0.011。手术组之间的体重减轻没有差异（p = 0.011），而对照组没有减轻体重。 SG组的平均基线TDI评分分别显着降低，分别为27.1±3.9和32.6±3.6（RYGB）和32.1±5.3（CG），而RYGB和CG患者在24周后没有变化。 SG组的TDI评分显着增加至31.1±3.5（p <0.01）。结论：我们的数据表明，大量的体重减轻本身并不影响嗅觉。但是，我们的研究结果表明，在胃袖切除术后，嗅觉感知得到了改善，而Roux-en-Y胃旁路术则没有。

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