From next-generation sequencing to nanopore sequencing technology: Paving the way to personalized genomic medicine

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From next-generation sequencing to nanopore sequencing technology: Paving the way to personalized genomic medicine

机译：From next-generation sequencing to nanopore sequencing technology: Paving the way to personalized genomic medicine

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High-throughput sequencing (HTS) technologies have revolutionized biomedical research. These breakthrough platforms have rapidly evolved from next-generation sequencing (NGS) or second-generation (2G) platforms to third-generation (3G) and fourth-generation (4G) sequencing machines. Sequencing, mapping and comparing the genomes of cells in healthy and disease states, cheaply, rapidly and accurately can alter the way clinicians think about how to treat patients shifting from traditional medicine to a genome-based era of preventive and therapeutic decisions. Particularly, in cancer with extreme genomic heterogeneity, applying HTS in cancer tissue samples from individual patients provides unprecedented power to reach personalized, highly effective approaches overcoming current therapeutic resistance.

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《Expert review of medical devices》 |2013年第1期|1-6|共6页
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正文语种英语
中图分类预防医学、卫生学;
关键词
biomarkers; cancer; clinical medicine; genome; high-throughput sequencing technologies; integrative genomic analysis; mutations; transcriptome;

From next-generation sequencing to nanopore sequencing technology: Paving the way to personalized genomic medicine

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