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机译:Structural basis for ligand promiscuity in cytochrome P450 3A4
AstraZeneca R&D Molndal, S-43183 Molndal, Sweden;
acs.unica.it;
drug metabolism; structural flexibility; x-ray crystallography; inhibitor; substrate; ALPHA-NAPHTHOFLAVONE; CRYSTAL-STRUCTURE; ACTIVE-SITE; RESOLUTION; BINDING; REFINEMENT; P4502B4; CYP3A4; COOPERATIVITY; TESTOSTERONE;