Non-invasive quantification of melanin in the stratum corneum: a novel indicator of skin lesions in pigmentation diseases

Matsunaka H.; Yamamoto Y.; Furukawa F.

首页> 外文期刊>Skin research and technology: official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) >Non-invasive quantification of melanin in the stratum corneum: a novel indicator of skin lesions in pigmentation diseases

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Non-invasive quantification of melanin in the stratum corneum: a novel indicator of skin lesions in pigmentation diseases

机译：角质层黑色素的非侵入性定量：色素沉着疾病皮肤病变的新指标

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Background/Purpose: Skin melanin content is an important indicator for ascertaining the pathology of skin pigmentation diseases, but its analysis necessitates a biopsy or other means of collecting tissue, posing a considerable burden to the patient, and making it difficult to observe how a given skin site changes over time. Here, we aimed to establish a non-invasive method for quantifying the eumelanin and pheomelanin content of the stratum corneum.

机译：背景/目的：皮肤黑色素含量是确定皮肤色素沉着疾病病理学的重要指标，但其分析需要活检或其他收集组织的方法，给患者带来相当大的负担，并且难以观察给定的皮肤部位如何随时间变化。在这里，我们旨在建立一种非侵入性的方法来量化角质层的真黑素和褐黑素含量。

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《Skin research and technology: official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)》 |2017年第1期|104-111|共8页
作者
Matsunaka H.; Yamamoto Y.; Furukawa F.;
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作者单位

Wakayama Med Univ, Dept Dermatol, 811-1 Kimiidera, Wakayama 6410012, Japan;

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原文格式 PDF
正文语种英语
中图分类皮肤病学与性病学;
关键词
melanin; eumelanin; pheomelanin; stratum corneum; HPLC; endothelin-1; interleukin-6;

机译：黑色素;真黑素;褐黑素;角质层;HPLC;内皮素-1;白细胞介素-6;

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Non-invasive quantification of melanin in the stratum corneum: a novel indicator of skin lesions in pigmentation diseases

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