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首页> 外文期刊>Journal of environmental science and health, Part A. Toxic/hazardous substances & environmental engineering >Combined ecotoxicity of binary zinc oxide and copper oxide nanoparticles to Scenedesmus obliquus
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Combined ecotoxicity of binary zinc oxide and copper oxide nanoparticles to Scenedesmus obliquus

机译：二元氧化锌和氧化铜纳米颗粒对斜角藻的综合生态毒性

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摘要

A combined ecotoxicity study was carried out with nano-zinc oxide (nZnO) and nano-copper oxide (nCuO) to freshwater algae Scenedesmus obliquus. Concentration-response analysis indicated that the dissolved metal fraction was not the major source of individual and combined toxicity of the metal-oxide nanoparticles (MONPs). Moreover, the contribution of the nCuO (based on metallic mass) to the combined toxicity was greater than that of the nZnO. The observed combined toxicity can be predicted by the pharmacological concepts of concentration addition (CA) and independent action (IA). Combined toxicity prediction (in terms of median effect concentration) based on both concepts tends to overestimate the overall observed toxicity of the MONP mixtures. CA was more accurate for predicting the combined toxicity than IA. It may be concluded that CA gives a valid estimation of the overall ecotoxicity for mixtures comprising of similar acting MONPs.
机译：用纳米氧化锌（nZnO）和纳米氧化铜（nCuO）对淡水藻类Scenedesmus obliquus进行了联合生态毒性研究。浓度响应分析表明，溶解的金属部分不是金属氧化物纳米颗粒（MONPs）的单个和综合毒性的主要来源。此外，nCuO（基于金属质量）对综合毒性的贡献大于nZnO。观察到的综合毒性可以通过浓度加成 （CA） 和独立作用 （IA） 的药理学概念来预测。基于这两个概念的综合毒性预测（以中位效应浓度计算）往往会高估MONP混合物的总体观察到的毒性。CA在预测联合毒性方面比IA更准确。可以得出结论，CA对由类似作用的MONPs组成的混合物的总体生态毒性进行了有效的估计。

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