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首页> 外文期刊>Neuromuscular disorders: NMD >Utility of skinfold thickness measurement in non-ambulatory patients with Duchenne muscular dystrophy
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Utility of skinfold thickness measurement in non-ambulatory patients with Duchenne muscular dystrophy

机译：皮褶厚度测量在杜氏肌营养不良症患者中非卧床的效用

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摘要

Nutritional disorders in Duchenne muscular dystrophy (DMD) worsen the medical condition. In particular, obesity is a serious problem that increases the risk of cardiomyopathy and affects nursing care. However, it is often difficult to evaluate body fatness in the advanced stages of DMD. Skinfold thickness measurement is a classical method to evaluate body fatness and is easily performed, even for bed-bound patients at home. We aimed to investigate the utility of skinfold thickness measurement in non-ambulatory DMD patients. Twenty-two patients with non-ambulatory, steroid-naive DMD ranging in age of 12-47 years were evaluated by body mass index (BMI), blood tests, measurement of triceps skinfold thickness (TSF), and abdominal computed tomography (CT) measurement of the areas of both subcutaneous and visceral fat. TSF showed good correlation with BMI (r = 0.80; p < 0.001), serum triglycerides (r = 0.67; p < 0.01), area of subcutaneous fat (r = 0.85; p < 0.0001), and area of visceral fat (r = 0.76; p < 0.0001). These results indicate the skinfold thickness measurement may be applicable as a screening tool in clinical practice where CT and magnetic resonance imaging assessment is often difficult in patients with advanced DMD.
机译：杜氏肌营养不良症 （DMD） 的营养失调会使医疗状况恶化。特别是，肥胖是一个严重的问题，会增加患心肌病的风险并影响护理。然而，在DMD的晚期阶段，通常很难评估体脂。皮褶厚度测量是评估体脂的经典方法，即使对于在家中卧床不起的患者也很容易进行。我们旨在研究皮褶厚度测量在非非卧床DMD患者中的效用。22 例年龄在 12-47 岁之间的非卧床、未使用类固醇的 DMD 患者通过体重指数 （BMI）、血液检查、肱三头肌皮褶厚度 （TSF） 测量和腹部计算机断层扫描 （CT） 测量皮下和内脏脂肪区域进行评估。TSF与BMI（r = 0.80;p < 0.001）、血清甘油三酯（r = 0.67;p < 0.01）、皮下脂肪面积（r = 0.85;p < 0.0001）和内脏脂肪面积（r = 0.76;p < 0.0001）具有良好的相关性。这些结果表明，皮褶厚度测量可能适用于临床实践中的筛查工具，因为晚期DMD患者通常难以进行CT和磁共振成像评估。

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