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首页> 外文期刊>Infectious disorders drug targets >Injecting illicit substances epidemic and infective endocarditis.
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Injecting illicit substances epidemic and infective endocarditis.

机译：注射违禁物质流行和感染性心内膜炎。

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摘要

Infective endocarditis (IE) is not the most frequent infection acquainted in intravenous drug abusers (IVDAs). On the other hand, all physicians should keep a high index of suspicion and always consider this possibility when they are dealing with an infectious process in this special population group. Since Sir William Osler, at the turn of the previous century, first described IE, there have been tremendous alterations in the very nature of this serious and possibly fatal disease. Right-sided endocarditis accounts for almost 10 of all IE episodes and has been correlated most commonly with injection of illicit drugs. However, recent reports have proposed that left-sided valves' participation is seen more often now than in the past. Although, the advances in medicine and especially modern imaging techniques have expanded our capacity to identify IE, there are still some gray areas in our ability to fully comprehend right-sided IE. Hussey et al. 1 were the first to distinguish IE as a distinct impediment of IV narcotics abuse in 1950. Although, many reports have been published since then arguing about the aspects of this medical entity, we will try here to comprehensively review the epidemiology and predisposing factors, clinical features and complications, diagnosis, treatment and prognosis of this disease, emphasizing on those distinctive or exclusive features seen in IE patients who are injecting illicit substances.
机译：感染性心内膜炎 （IE） 不是静脉注射药物滥用者 （IVDA） 中最常见的感染。另一方面，所有医生在处理这一特殊人群的感染过程时都应保持高度怀疑，并始终考虑这种可能性。自从威廉·奥斯勒爵士（Sir William Osler）在上个世纪初首次描述IE以来，这种严重且可能致命的疾病的性质发生了巨大变化。右侧心内膜炎占所有 IE 发作的近 10%，并且最常与注射违禁药物相关。然而，最近的报告表明，现在比过去更频繁地看到左侧瓣膜的参与。尽管医学的进步，尤其是现代成像技术的进步扩大了我们识别IE的能力，但在我们完全理解右侧IE的能力方面仍然存在一些灰色地带。Hussey等[1]于1950年率先将IE区分为静脉麻醉品滥用的明显障碍。尽管从那时起已经发表了许多关于该医学实体方面的报告，但我们将在这里尝试全面回顾该疾病的流行病学和易感因素、临床特征和并发症、诊断、治疗和预后，强调注射非法药物的 IE 患者所见的独特或排他性特征。

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