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首页> 外文期刊>Journal of environmental science and health, Part A. Toxic/hazardous substances & environmental engineering >Single and joint oxidative stress of cadmium and phenanthrene on the Bivalve Anadara subcrenata
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Single and joint oxidative stress of cadmium and phenanthrene on the Bivalve Anadara subcrenata

机译：镉和菲对双壳类Anadara subcrenata的单一和联合氧化应激

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Single and joint oxidative stress of cadmium (Cd) and phenanthrene (Phe) on Anadara subcrenata were investigated under laboratory conditions with biomarkers such as reactive oxygen species (ROS), malondialdehyde (MDA), superoxide dismutase (SOD) and total antioxidant capacity (TAOC). The results indicated that the ROS level in Anadara subcrenata exposed to Cd and Phe significantly (P 0.05) increased during the early exposure stage, and the TAOC level and SOD activity were induced as the response of the antioxidant defense system, and this followed a damage, recovery or acclimation event. The MDA content was negatively correlated with SOD activity. As the time went on, the ROS level decreased gradually and was close to that in the control after 9 days; the TAOC level decreased accordingly, but the recovery rate of the SOD activity was slower than that of the TAOC level. High concentrations of Cd or Phe had a stronger oxidative stress effect on Anadara subcrenata. Phe had a stronger effect on the SOD activity of Anadara subcrenata. The joint effects of Cd and Phe on the levels of ROS and TAOC, SOD activity and MDA content in Anadara subcrenata are dependent on their concentration combination, which were called the double-dose dependent effects and time-dependent effects, respectively. The binary mixture treatments of 477.33 mu g/L Cd and 48.08 mu g/L Phe had the highest oxidative stress on Anadara subcrenata.
机译：采用活性氧（ROS）、丙二醛（MDA）、超氧化物歧化酶（SOD）和总抗氧化能力（TAOC）等生物标志物，研究了镉（Cd）和菲（Phe）对Anadara subcrenata的单次和联合氧化应激。结果表明，暴露于Cd和Phe的Anadara subcrenata的ROS水平在暴露初期显著升高（P < 0.05），TAOC水平和SOD活性作为抗氧化防御系统的响应被诱导，并随后发生损伤、恢复或驯化事件。MDA含量与SOD活性呈负相关。随着时间的流逝，ROS水平逐渐下降，9天后接近对照组;TAOC水平随之降低，但SOD活性的恢复速度慢于TAOC水平。高浓度的Cd或Phe对Anadara subcrenata具有更强的氧化应激作用。Phe对Anadara subcrenata的SOD活性影响更强。Cd和Phe对Anadara subcrenata中ROS和TAOC、SOD活性和MDA含量水平的联合影响取决于它们的浓度组合，分别称为双剂量依赖效应和时间依赖效应。477.33 μ g/L Cd和48.08 mu g/L Phe的二元混合处理对Anadara subcrenata的氧化应激最高。

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