The NHLBI model: A 25 year history

Lawrence Friedman

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The NHLBI model: A 25 year history

机译：NHLBI 模型：25 年的历史

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AbstractAlthough newer techniques and procedures have been developed, many of the clinical trial design and monitoring concepts used today in the NHLBI were implemented 25 years ago. Among these are the organizational structure of multicentre trials and the use of an independent data monitoring committee. Examples of data monitoring committee discussions and decisions are provided.

机译：摘要尽管已经开发了更新的技术和程序，但目前在NHLBI中使用的许多临床试验设计和监测概念都是在25年前实施的。其中包括多中心试验的组织结构和独立数据监测委员会的使用。提供了数据监测委员会讨论和决定的实例。

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《statistics in medicine》 |1993年第5‐6期|425-431|共页
作者
Lawrence Friedman;
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The NHLBI model: A 25 year history

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