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Use of Optical Coherence Tomography in the Diagnosis and Management of Uveitis

机译:光学相干断层扫描在葡萄膜炎的诊断和治疗中的应用

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摘要

Uveitis is a challenging disease. It represents a major cause of ocular morbidity worldwide. More than half of all patients with uveitis develop sight threatening complications related to their disease, and up to 35% of patients suffer severe visual impairment. Uveitis and its complications are responsible for 5% to 10% of all causes of legal blindness in developed countries. The causes of uveitis are numerous, and include infectious conditions, autoimmune diseases, trauma, and tumors (masquerade syndrome). To develop an accurate differential diagnosis, clinicians must consider all available information, including the patient history, anatomic location of the inflammation (anterior or posterior), character (granulomatous vs. nongranulomatous), laterality, and chron-icity of inflammation. Moreover, diagnostic tools, such as fluorescein angiography (FA), indocyanine green angiography, optical coherence tomography (OCT), and ultrasound, play an important role in the diagnosis and in the management of the uveitis.
机译:葡萄膜炎是具有挑战性的疾病。它代表了全世界眼病的主要原因。在所有葡萄膜炎患者中,超过一半的人会出现与其疾病相关的威胁视力的并发症,并且多达35%的患者患有严重的视力障碍。在发达国家,葡萄膜炎及其并发症占所有导致法律失明的原因的5%至10%。葡萄膜炎的病因很多,包括感染性疾病,自身免疫性疾病,创伤和肿瘤(化装舞会综合症)。为了进行准确的鉴别诊断,临床医生必须考虑所有可用信息,包括患者的病史,炎症的解剖位置(前或后),特征(肉芽肿与非肉芽肿),炎症的偏侧性和时效性。此外,诸如荧光素血管造影(FA),吲哚菁绿色血管造影,光学相干断层扫描(OCT)和超声之类的诊断工具在葡萄膜炎的诊断和管理中起着重要的作用。

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