The Significance of Anticardiolipin Antibodies in Patients with Vasculitis

Mary Gantcheva

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The Significance of Anticardiolipin Antibodies in Patients with Vasculitis

机译：抗心磷脂抗体在血管炎患者中的意义

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We evaluate the incidence of serum anticardiolipin antibodies in patients with different types of vasculitides and vasculopathies and describe clinical, histological and laboratory specificity and disease course in correlation with their positivity. We conclude that they activate endothelial cells in both occlusive and inflammatory vascular diseases, aggravate skin symptoms, but are not related to advanced systemic involvement and poor prognosis. They represent skin ulcerations on acral sites in lupus erythematosus and have a predictive role for thrombosis. Livedo vasculitis may be a clinical sign of antiphospholipid syndrome.

机译：我们评估了不同类型血管炎和血管病患者血清抗心磷脂抗体的发生率，并描述了临床、组织学和实验室特异性以及与其阳性相关的病程。我们得出的结论是，它们在闭塞性和炎症性血管疾病中激活内皮细胞，加重皮肤症状，但与晚期全身受累和不良预后无关。它们代表红斑狼疮肢端部位的皮肤溃疡，对血栓形成具有预测作用。Livedo血管炎可能是抗磷脂综合征的临床体征。

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《Acta morphologica et anthropologica》 |2018年第4期|38-43|共6页
作者
Mary Gantcheva;
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作者单位

Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Science, Sofia, Bulgaria;

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原文格式 PDF
正文语种英语
中图分类细胞生物学;
关键词
Anticardiolipin antibodies; vasculitis; vasculopathy; antiphospholipid syndrome; livedo vasculitis.;

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2. Well‐imaged large vessel vasculitis attributed to anticardiolipin antibody [J] . W. Neal Roberts, Jonathan H. Demeo, Sarah A. Breitbach Arthritis and Rheumatism . 1994,第8期

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The Significance of Anticardiolipin Antibodies in Patients with Vasculitis

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