Exploring the Electrophysiologic and Hemodynamic Effects of Cardiac Resynchronization Therapy From Bench to Bedside and Vice Versa

Schreurs Rick; Wiegerinck Rob F.; Prinzen Frits W.

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Exploring the Electrophysiologic and Hemodynamic Effects of Cardiac Resynchronization Therapy From Bench to Bedside and Vice Versa

机译：探索从工作台到床边的心脏再同步化治疗的电生理学和血流动力学效应，反之亦然

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Cardiac resynchronization therapy (CRT) is an important therapy for heart failure patients with prolonged QRS duration. In patients with left bundle branch block the altered left ventricular electrical activation results in dyssynchronous, inefficient contraction of the left ventricle. CRT aims to reverse these changes and to improve cardiac function. This article explores the electrophysiologic and hemodynamic changes that occur during CRT in patient and animal studies. It also addresses how novel techniques, such as multipoint and endocardial pacing, can further improve the electromechanical response.

机译：心脏再同步化疗法（CRT）是 QRS 持续时间延长的心力衰竭患者的重要治疗方法。在左束支传导阻滞患者中，左心室电激活的改变导致左心室收缩不同步、低效。CRT旨在逆转这些变化并改善心脏功能。本文探讨了患者和动物研究中 CRT 期间发生的电生理和血流动力学变化。它还讨论了新技术（例如多点和心内膜起搏）如何进一步改善机电反应。

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来源
《Heart failure clinics》 |2017年第1期|43-52|共12页
作者
Schreurs Rick; Wiegerinck Rob F.; Prinzen Frits W.;
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作者单位

Maastricht Univ, Cardiovasc Res Inst Maastricht, Dept Physiol, Maastricht, Netherlands;

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原文格式 PDF
正文语种英语
中图分类心脏、血管（循环系）疾病;
关键词
Left bundle branch block; Cardiac resynchronization therapy; Animal research; Electrophysiology; Hemodynamics;

机译：左束支传导阻滞;心脏再同步化治疗;动物研究;电生理学;血流动力学;

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Exploring the Electrophysiologic and Hemodynamic Effects of Cardiac Resynchronization Therapy From Bench to Bedside and Vice Versa

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