...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of the South African Veterinary Association >Efficacy of a genotype 2 Newcastle disease vaccine (AvinewReg.) against challenge with highly virulent genotypes 5d and 3d.
【24h】

Efficacy of a genotype 2 Newcastle disease vaccine (AvinewReg.) against challenge with highly virulent genotypes 5d and 3d.

机译：基因型 2 新城疫疫苗 （AvinewReg.） 对高毒性基因型 5d 和 3d 攻击的疗效。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Since 2002, following its introduction, the lineage 5d Newcastle disease virus (so-called Goose paramyxovirus - GPMV) strain has caused numerous disease outbreaks among commercial and backyard poultry in South Africa, raising questions about the ability of commercially available Newcastle disease vaccines to fully protect poultry against the strain. This study aimed to determine whether there are differences in the level of protection offered by AvinewReg. Newcastle disease vaccine against GPMV virus as compared with a 3d Newcastle disease virus isolated in South Africa in 1993 (Rainbow challenge virus - RCV) strain. Six groups of 10-day-old, specific pathogen-free chickens were vaccinated with doses of 1030, 104.5 and 106.0 EID50 of AvinewReg. vaccine and challenged at 4 weeks of age intramuscularly at a dose of 105.3 EID50/0.2 ml/bird of GPMV and RCV No statistically significant difference could be found in the protection offered by AvinewReg. vaccine against GPMV as compared to RCV challenge. The protection offered against the ND challenge was found to be dose dependent. At the recommended field dose of 106.0 EID50 the vaccine gave 100 protection from mortality against both the challenge viruses, but not against infection and replication of the viruses, as gross lesions were evident even in apparently healthy birds that survived the challenge. The protective dose (PD90) of the AvinewReg. vaccine against GPMV challenge was calculated at 104.38 and against that of RCV at 104.43.

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号