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Steroids in aquatic invertebrates.

机译：水生无脊椎动物中的类固醇。

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摘要

Steroid molecules are present in all invertebrates, and some of them have established hormonal roles: this is the case for ecdysteroids in arthropods and, to a lesser extent, for vertebrate-type steroids in molluscs. Steroids are not only hormones, they may also fulfill many other functions in chemical communication, chemical defense or even digestive physiology. The increasing occurrence of endocrine disruption problems caused by environmental pollutants, which interfere in particular with reproductive physiology of vertebrates but also of invertebrates has made necessary to better understand the endocrine physiology of the latter and the role of steroids in these processes. So many attempts are being made to better understand the endocrine roles of steroids in arthropods and molluscs, and to establish whether they also fulfill similar functions in other invertebrate phyla. At the moment, both the precise identification of these steroids, the determination of their origin (endogenous versus exogenous)and of their mechanism of action are under active investigation. This research takes profit of the development of genome sequencing programs on many invertebrate species, which allow the identification of receptors and/or biosynthetic enzymes, when related to their vertebrate counterparts, but the story is not so simple, as will be exemplified by estrogen receptors of molluscs.
机译：类固醇分子存在于所有无脊椎动物中，其中一些具有确定的激素作用：节肢动物中的蜕皮类固醇和软体动物中的脊椎动物类固醇都属于这种情况。类固醇不仅是激素，还可以在化学交流，化学防御甚至消化生理学中发挥许多其他功能。由环境污染物引起的内分泌干扰问题的发生率越来越高，这尤其会干扰脊椎动物的生殖生理以及无脊椎动物的生殖生理，因此有必要更好地了解后者的内分泌生理以及类固醇在这些过程中的作用。人们进行了许多尝试，以更好地了解类固醇在节肢动物和软体动物中的内分泌作用，并确定它们在其他无脊椎动物门中是否也具有类似的功能。目前，正在积极研究这些类固醇的精确鉴定，其来源（内源性还是外源性）的确定及其作用机理。这项研究从开发许多无脊椎动物物种的基因组测序程序中获利，这些程序可以鉴定与脊椎动物对应的受体和/或生物合成酶，但故事并非如此简单，以雌激素受体为例软体动物。

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