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首页> 外文期刊>The Journal of Bone and Joint Surgery. British VolumecBritish Orthopaedic Association , Australian Orthopaedic Association , Canadian Orthopaedic Association . . . [et al] >The use of a biodegradable mesh plate to augment grafting of an acetabular defect: Laboratory investigation and clinical pilot study
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The use of a biodegradable mesh plate to augment grafting of an acetabular defect: Laboratory investigation and clinical pilot study

机译：使用可生物降解的网板增强髋臼缺损的移植：实验室调查和临床试点研究

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摘要

We used a biodegradable mesh to convert an acetabular defect into a contained defect in six patients at total hip replacement. Their mean age was 61 years (46 to 69). The mean followup was 32 months (19 to 50). Before clinical use, the strength retention and hydrolytic in vitro degradation properties of the implants were studied in the laboratory over a two-year period. A successful clinical outcome was determined by the radiological findings and the Harris hip score. All the patients had a satisfactory outcome and no mechanical failures or other complications were observed. No protrusion of any of the impacted grafts was observed beyond the mesh. According to our preliminary laboratory and clinical results the biodegradable mesh is suitable for augmenting uncontained acetabular defects in which the primary stability of the implanted acetabular component is provided by the host bone. In the case of defects of the acetabular floor this new application provides a safe method of preventing graft material from protruding excessively into the pelvis and the mesh seems to tolerate bone-impaction grafting in selected patients with primary and revision total hip replacement.
机译：我们使用可生物降解的网片将 6 名患者的全髋关节置换术中的髋臼缺损转化为包含的缺损。他们的平均年龄为61岁（46至69岁）。平均随访时间为32个月（19至50个月）。在临床使用之前，在实验室中研究了植入物的强度保持和体外水解降解性能，为期两年。成功的临床结果取决于放射学检查结果和 Harris 髋关节评分。所有患者均获得满意的结果，未观察到机械故障或其他并发症。在网格之外没有观察到任何受影响的移植物的突出。根据我们的初步实验室和临床结果，可生物降解的网片适用于增强未包含的髋臼缺损，其中植入的髋臼组件的主要稳定性由宿主骨提供。在髋臼底缺损的情况下，这种新应用提供了一种安全的方法，可以防止移植物材料过度突出到骨盆中，并且网片似乎可以耐受骨嵌塞移植，适用于初次和翻修全髋关节置换术的选定患者。

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