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Sleep and Hormonal Changes in Aging

机译:衰老中的睡眠和荷尔蒙变化

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摘要

Age-related sleep and endocrinometabolic alterations frequently interact with each other. For many hormones, sleep curtailment in young healthy subjects results in alterations strikingly similar to those observed in healthy old subjects not submitted to sleep restriction. Thus, recurrent sleep restriction, which is currently experienced by a substantial and rapidly growing proportion of children and young adults, might contribute to accelerate the senescence of endocrine and metabolic function. The mechanisms of sleep-hormonal interactions, and therefore the endocrinometabolic consequences of age-related sleep alterations, which markedly differ from one hormone to another, are reviewed in this article.
机译:与年龄有关的睡眠和内分泌代谢改变经常相互影响。对于许多激素而言,减少年轻健康受试者的睡眠会导致与未接受睡眠限制的健康老年受试者观察到的变化惊人地相似。因此,目前大量和迅速增长的儿童和年轻人所经历的反复睡眠限制可能有助于加速内分泌和代谢功能的衰老。本文综述了睡眠-激素相互作用的机制,以及与年龄有关的睡眠变化的内分泌代谢后果,这种变化在一种激素之间存在显着差异。

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