Complications of Diabetes Therapy

CorathersS.D.; PeavieS.; SalehiM.

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Complications of Diabetes Therapy

机译：糖尿病治疗的并发症

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Current strategies for the treatment of type 2 diabetes mellitus promote individualized plans to achieve target glucose levels on a patient-by-patient basis while minimizing treatment related risks. Maintaining glycemic control over time is a significant challenge because of the progressive nature of diabetes as a result of declining β-cell function. This article identifies complications of non-insulin treatments for diabetes. The major classes of medications are reviewed with special focus on target population, mechanism of action, effect on weight, cardiovascular outcomes and additional class-specific side effects including effects on bone. Effects on β-cell function are also highlighted.

机译：当前用于治疗2型糖尿病的策略促进了个性化计划，以在逐个患者的基础上实现目标血糖水平，同时将与治疗相关的风险降至最低。随着时间的推移保持血糖控制是一项重大挑战，这是由于β细胞功能下降导致糖尿病的进行性所致。本文确定了非胰岛素治疗糖尿病的并发症。审查了主要的药物类别，特别关注目标人群，作用机理，对体重的影响，心血管结局以及其他类别特异性的副作用，包括对骨骼的影响。还突出了对β细胞功能的影响。

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《Endocrinology and Metabolism Clinics of North America》 |2013年第4期|共24页
作者
CorathersS.D.; PeavieS.; SalehiM.;
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正文语种 eng
中图分类内分泌腺疾病及代谢病;
关键词
β-cell function; Cardiovascular outcomes; Diabetes; Treatment complications;

机译：β细胞功能;心血管预后;糖尿病;治疗并发症;

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1. Effects of prior intensive insulin therapy on cardiac autonomic nervous system function in type 1 diabetes mellitus: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC). [J] . Pop Busui R, Low PA, Waberski BH, Circulation: An Official Journal of the American Heart Association . 2009,第22期

机译：先前密集胰岛素治疗对1型糖尿病心脏自主神经系统功能的影响：糖尿病控制和并发症糖尿病干预和并发症研究的流行病学（DCCT / edic）。
2. Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. [J] . The New England journal of medicine . 2000,第6期

机译：经过强化治疗的四年后，1型糖尿病患者的视网膜病变和肾病。糖尿病干预与并发症研究小组的糖尿病控制与并发症试验/流行病学。
3. Effects of Prior Intensive Insulin Therapy and Risk Factors on Patient-Reported Visual Function Outcomes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Cohort [J] . Gubitosi-Klug Rose A., Sun Wanjie, Cleary Patricia A., JAMA ophthalmology . 2016,第2期

机译：先前的胰岛素强化治疗和危险因素对患者报告的糖尿病控制和并发症视力功能结局的影响糖尿病干预和并发症（DCCT / EDIC）队列的试验/流行病学
4. Brief Counselling with Self-evaluation Drug Use Sheet To Improve the effectivity of Drug Therapy in Diabetes Mellitus with Hypertension Complication Outpatients [C] . Akrom, Sari Ramadhani, Zuhraf Ginanjar Saputri Ahmad Dahlan International Conference Series on Pharmacy and Health Science . 2019

机译：与自我评价药物使用表的简要咨询，以提高糖尿病患者患有高血压并发症外分的糖尿病的有效性
5. Diabetes susceptibility polymorphisms and risk of prediabetes and diabetes complications in the atherosclerosis risk in communities (ARIC) study. [D] . Yan, Yu. 2009

机译：糖尿病易感性多态性与糖尿病前期和糖尿病并发症的风险在社区的动脉粥样硬化风险中的研究（ARIC）。
6. EFFECT OF INTENSIVE GLYCEMIC THERAPY ON ERECTILE FUNCTION IN MEN WITH TYPE 1 DIABETES IN THE DIABETES CONTROL AND COMPLICATIONS TRIAL/EPIDEMIOLOGY OF DIABETES INTERVENTIONS AND COMPLICATIONS STUDY [O] . Hunter Wessells, David F. Penson, Patricia Cleary, -1

机译：强化血糖治疗对糖尿病患者糖尿病患者勃起功能的影响及糖尿病干预糖尿病患者及并发症研究
7. Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: relevance of glycated collagen products versus HbA1c as markers of diabetic complications. DCCT Skin Collagen Ancillary Study Group. Diabetes Control and Complications Trial [O] . V. M. Monnier, O. Bautista, D. Kenny, 1999

机译：皮肤胶原蛋白糖浆，甘油氧化和交联在具有1型糖尿病的长期密集患者的受试者中较低：糖化胶原产品与HBA1c作为糖尿病并发症标记的相关性。 DCCT皮肤胶原蛋白辅助研究组。糖尿病控制和并发症试验
8. Effects of Intensive Diabetes Therapy on Neuropsychological Function in Adults inthe Diabetes Control and Complications Trial. Analysis Documentation [R] . 1997

机译：强化糖尿病治疗对糖尿病控制和并发症患者神经心理功能的影响。分析文档

Complications of Diabetes Therapy

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