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Anaplastic thyroid cancer.

机译:间变性甲状腺癌。

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摘要

Anaplastic thyroid cancer is an uncommon, typically lethal malignancy of older adults with no effective systemic therapy. The mean survival time is usually less than 6 months from the time of diagnosis and, unfortunately, this outcome is not fundamentally altered by available treatments. Histologic tissue confirmation is recommended if the diagnosis is not absolutely certain to exclude tumors with better prognosis or that require different treatment. Patency of the airway should be kept in mind throughout the patient's course and individuals with impending airway obstruction, in the absence of imminent death from other sites of disease, should be considered for a tracheostomy to secure the airway. Enrollment in meaningful clinical trials should be given the highest priority at all decision points.
机译:间变性甲状腺癌是没有有效全身疗法的老年人的罕见,典型的致死性恶性肿瘤。自诊断之日起,平均生存时间通常少于6个月,不幸的是,这种结果并没有从根本上改变现有的治疗方法。如果不能绝对肯定地排除诊断以排除预后较好或需要不同治疗的肿瘤,则建议组织学确认。在整个患者病程中应牢记气道通畅,在没有其他疾病即将死亡的情况下,应考虑将有气道阻塞的个体进行气管切开术以保护气道。在所有决策点上,都应优先考虑进行有意义的临床试验。

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