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首页> 外文期刊>Epilepsia: Journal of the International League against Epilepsy >Surgical treatment of a case of early infantile epileptic encephalopathy with suppression-bursts associated with focal cortical dysplasia.
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Surgical treatment of a case of early infantile epileptic encephalopathy with suppression-bursts associated with focal cortical dysplasia.

机译：伴有局灶性皮质发育异常的抑制性猝发的早期婴儿癫痫性脑病的外科治疗。

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摘要

We report a surgically treated case of early infantile epileptic encephalopathy (EIEE) with suppression-bursts associated with focal cortical dysplasia. Tonic-clonic seizures followed by a series of spasms occurred about a hundred times a day at a few days of age. Interictal electroencephalogram (EEG) revealed a suppression-burst pattern that was predominant in the left hemisphere. Magnetic resonance imaging (MRI) suggested focal cortical dysplasia in the left prefrontal area. Combination therapies with antiepileptic treatments showed only partial efficacy. The patient underwent lesionectomy at age 4 months, after which he gradually showed psychomotor development and a decrease of spasms to 0-2 series daily. In cases of EIEE with focal cortical dysplasia, surgical treatment may have beneficial effects on both psychomotor development and seizure control.
机译：我们报告了手术治疗的早期婴儿癫痫性脑病（EIEE），伴有局灶性皮质发育异常的抑制性猝发。在几天后的一天中，强直性阵挛性癫痫发作随后发生一系列痉挛。发作间脑电图（EEG）显示左半球主要为抑制-爆发模式。磁共振成像（MRI）提示左额叶前额区有局灶性皮质发育异常。抗癫痫治疗的联合疗法仅显示部分疗效。该患者在4个月大时进行了病灶切除术，此后他逐渐表现出精神运动发育并将痉挛减少至每天0-2系列。对于伴有局灶性皮质发育异常的EIEE，手术治疗可能对精神运动发育和癫痫发作控制均具有有益的作用。

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