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首页> 外文期刊>European journal of neurology: the official journal of the European Federation of Neurological Societies >Intracranial artery dissection
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Intracranial artery dissection

机译：颅内动脉夹层

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摘要

The aim of this narrative review is to evaluate the pathogenesis, clinical features, diagnosis, treatment and prognosis of intracranial artery dissection (IAD). IAD is a rare and often unrecognized cause of stroke or subarachnoid haemorrhage (SAH), especially in young adults. Two types of IAD can be identified: a subintimal or subadventitial dissection. It is suggested that a subintimal dissection results in luminal stenosis, thromboembolism and subsequently cerebral ischaemia, whilst a subadventitial IAD could result in the formation of a pseudo-aneurysm and compression on brainstem or cranial nerves. Rupture of such a dissecting aneurysm causes SAH. The exact cause of IAD remains unknown but several factors are associated with its development. Diagnosis is based on clinical presentation and specific features seen on multimodal neuroimaging. The management of IAD depends on the clinical presentation. In the case of cerebral ischaemia, anticoagulants or antiplatelet agents are used, whilst in the case of SAH endovascular treatment is primarily advocated. Prognosis depends on clinical presentation.
机译：这篇叙述性综述的目的是评估颅内动脉夹层（IAD）的发病机制，临床特征，诊断，治疗和预后。 IAD是中风或蛛网膜下腔出血（SAH）的罕见原因，通常是无法识别的原因，尤其是在年轻人中。可以确定两种类型的IAD：内膜下或膜下剥离。提示内膜下剥离可导致管腔狭窄，血栓栓塞和随后的脑缺血，而外膜下IAD可导致假性动脉瘤的形成并压迫脑干或颅神经。这种夹层动脉瘤破裂会引起SAH。 IAD的确切病因尚不清楚，但有几个因素与其发展有关。诊断基于临床表现和多模式神经影像学所见的特定特征。 IAD的管理取决于临床表现。在脑缺血的情况下，使用抗凝剂或抗血小板药，而在SAH情况下，主要提倡血管内治疗。预后取决于临床表现。

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