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首页> 外文期刊>European journal of gastroenterology and hepatology >Noninvasive assessment of hepatic lipid composition: advancing understanding and management of fatty liver disorders
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Noninvasive assessment of hepatic lipid composition: advancing understanding and management of fatty liver disorders

机译：肝脂质成分的非侵入性评估：增进对脂肪肝疾病的了解和管理

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Nonalcoholic fatty liver is frequently observed in obese individuals, yet the factors that predict its development and progression to liver disease are poorly understood. We proposed that proton magnetic resonance spectroscopy ('H-MRS) might allow noninvasive assessment of hepatic lipid composition. Lipid saturation (SI) and polyunsa-turation (PUI) indices measured by H-MRS were in agreement with those expected in oils of known compositioriisHepatic triglyceride concentration (HTGC) and composition were then measured in healthy lean (LEAN) men, obese men with normal HTGC (OB), and obese men with hepatic steatosis (OB + HS).
机译：非酒精性脂肪肝经常在肥胖者中观察到，但对预测其发展和进展为肝病的因素知之甚少。我们建议质子磁共振波谱（'H-MRS）可能允许无创评估肝脂质成分。通过H-MRS测量的血脂饱和度（SI）和多不饱和指数（PUI）与已知复合油中的预期值一致。然后在健康的瘦肉（LEAN）男性，肥胖的男性中测量甘油三酸酯的浓度（HTGC）和组成。 HTGC（OB）正常，肥胖的男性患有肝脂肪变性（OB + HS）。

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