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首页> 外文期刊>European journal of gynaecological oncology >Which is the appropriate surgical procedure for Stage I endometrial carcinoma?
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Which is the appropriate surgical procedure for Stage I endometrial carcinoma?

机译：I期子宫内膜癌合适的手术方法是什么？

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Objective: To study the appropriate surgical procedure for Stage I endometrial carcinoma (EC), the clinical and pathological features and prognosis factors, as well as types were analyzed retrospectively. Materials and Methods: This is a retrospective study of 277 patients with early-stage EC in clinical Stages I that received surgery between January 2000 and March 2008. The appropriate surgical procedures were divided into three types (procedure I-III: hysterectomy with or without ovary preservation, subradical hysterectomy plus pelvic lymph node biopsy, and radical hysterectomy pelvic plus lymphadenectomy) according to the clinical stage. Results: Tumor invasion of the cervix and deep muscularis as well as the parametrium, EC Stage Ib, grade 3 and ascites had carcinoma cells, were high-risk factors of EC metastasis to the retroperitoneum (p < 0.05). The ovarian preservation of EC Stage Ia had no effect on overall survival. The three types of procedure for the EC Stage Ia were not correlated significantly to the three-year and five-year survival rates. The three-year and five-year survival rates of three surgical procedures for the EC Stage Ib were significantly correlated. The survival rates of surgical procedures II and III were significantly higher than that of procedure I (P < 0.05). Conclusion: Subradical hysterectomy plus pelvic lymph node biopsy was recommended for EC Stage Ib with high-risk factors. There was no evidence of benefit in terms of overall or recurrence-free survival for radical hysterectomy plus pelvic lymphadenectomy in women with Stage I EC.
机译：目的：回顾性分析I期子宫内膜癌（EC）的合适手术方法，探讨其临床，病理特征，预后因素以及类型。材料与方法：这是一项回顾性研究，对2000年1月至2008年3月间接受手术的277例处于临床I期的早期EC患者进行了回顾性研究。适当的手术程序分为三种类型（I-III程序：有或无子宫切除术保留卵巢，根治性子宫切除+盆腔淋巴结活检和根治性子宫切除术+盆腔淋巴结切除术）。结果：子宫颈和深层肌瘤以及子宫内膜的肿瘤浸润，EC Stage Ib，3级和腹水均带有癌细胞，是EC转移至腹膜后的高危因素（p <0.05）。 EC期Ia的卵巢保存对总体生存没有影响。 EC期Ia的三种手术类型与三年和五年生存率没有显着相关性。 EC期Ib的三种手术方法的三年和五年生存率显着相关。手术II和III的生存率显着高于手术I（P <0.05）。结论：对于高危因素的EC期Ib，建议行根治性子宫切除术和盆腔淋巴结活检。对于I期EC的女性，尚无证据表明根治性子宫切除联合盆腔淋巴结切除对总体生存或无复发生存有帮助。

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