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首页> 外文期刊>Journal of Physics, D. Applied Physics: A Europhysics Journal >Fretting wear behaviour of hydroxyapatite-titanium composites in simulated body fluid, supplemented with 5 g l~(-1) bovine serum albumin
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Fretting wear behaviour of hydroxyapatite-titanium composites in simulated body fluid, supplemented with 5 g l~(-1) bovine serum albumin

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摘要

Damaged articulating joints can be repaired or replaced with synthetic biomaterials, which can release wear debris due to articulation, leading to the osteolysis. In a recent work, it has been shown that it is possible to achieve a better combination of flexural strength/fracture toughness as well as in vitro bioactivity and cytocompatibility properties in spark plasma sintered hydroxyapatite-titanium (HA-Ti) composites. Although hydroxyapatite and titanium are well documented for their good biocompatibility, nanosized hydroxyapatite (HA) and titanium (Ti) particles can cause severe toxicity to cells. In order to address this issue, fretting wear study of HA-Ti composites under dry and wet (1× SBF, supplemented with 5 g l~(-1) bovine serum albumin (BSA)) condition was performed to assess the wear resistance as well as wear debris formation, in vitro. The experimental results reveal one order of magnitude lower wear rate for HA-10 wt Ti (7.5 × 10~(-5) mm3 N~(-1) m~(-1)) composite than monolithic HA (3.9 × 10 ~(-4) mm3 N~(-1) m~(-1)) in simulated body fluid. The difference in the tribological properties has been analyzed in the light of phase assemblages and mechanical properties. Overall, the results suggest the potential use of HA-Ti composites over existing HA-based biocomposites in orthopedic as well as dental applications.

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