...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>international journal of advanced biotechnology and research >Evaluation ofOxidative Stress Indices afterExposure to MalathionProtective Effects of VitaminC inOvarian Tissue ofAdult FemaleRats
【24h】

Evaluation ofOxidative Stress Indices afterExposure to MalathionProtective Effects of VitaminC inOvarian Tissue ofAdult FemaleRats

机译：

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background:Malathion is an organophosphate pesticide which is known to induce oxidative stress in the targettissues such as the reproductive system.The aim of present study was to evaluate the effects of malathion onmalondialdehyde(MDA) and glutathione(GSH) levels in female rat reproductive tissue (ovary) and to assess theprotective role of vitamin C.Materials and Methods:In this experimental study, 30 adult female Wistarrats (weight range: 200-250 g) weredivided into five groups,consisting of six rats: control group (no interventions), sham group (normal saline),experimental group 1 (malathion+normal saline 50 mg/kg ), experimental group 2 (200 mg/kg of vitamin C), andexperimental group 3 (similar dosesof vitamin C and malathion). The animals were scarified after two weeks andMDA as a marker of lipid peroxidation and GSH content were measured in ovarian tissue.Results: Malathion reduced GSH content and increased MDA level in ovary compared with the control group(P<0.001). Vitamin C plus malathion increased GSH content but decreased malathion induced MDA elevation inrat ovarian tissue.Conclusion: Oxidative stress contributes to DZN-induced ovarian toxicity.Our results concluded that vitamin Emay have a protective role in this toxicity.

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号