Statistical design and the analysis of gene expression microarray data

M. KATHLEEN KERR; GARY A. CHURCHILL

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Statistical design and the analysis of gene expression microarray data

机译：基因表达芯片数据的统计设计与分析

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Gene expression microarrays are an innovative technology with enormous promise to help geneticists explore and understand the genome. Although the potential of this technology has been clearly demonstrated, many important and interesting statistical questions persist. We relate certain features of microarrays to other kinds of experimental data and argue that classical statistical techniques are appropriate and useful. We advocate greater attention to experimental design issues and a more prominent role for the ideas of statistical inference in microarray studies.

机译：基因表达微阵列是一项创新技术，具有巨大的前景，可帮助遗传学家探索和理解基因组。尽管已经清楚地证明了该技术的潜力，但仍然存在许多重要且有趣的统计问题。我们将微阵列的某些特征与其他种类的实验数据相关联，并认为经典的统计技术是适当且有用的。我们主张更多地关注实验设计问题，并在微阵列研究中为统计推断的思想发挥更重要的作用。

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《Genetical Research》 |2007年第6期|共6页
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M. KATHLEEN KERR; GARY A. CHURCHILL;
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正文语种 eng
中图分类遗传学;
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1. Proper experimental design and sound statistical inference win every time: a commentary on 'Statistical design and the analysis of gene expression microarray data' by M. Kathleen Kerr and Gary A. Churchill [J] . Doerge R W Genetical Research . 2007,第5a6期

机译：正确的实验设计和可靠的统计推断每次都赢：M。Kathleen Kerr和Gary A. Churchill对“统计设计和基因表达微阵列数据分析”的评论
2. Statistical Approaches in the Analysis of Gene Expression Data Derived from Bone Regeneration Specific cDNA Microarrays [J] . Jungnam Joo, Hongshik Ahn, Frank Lombardo, Journal of biopharmaceutical statistics . 2004,第3期

机译：骨再生特异性cDNA基因芯片的基因表达数据分析中的统计方法。
3. Statistical Approaches in the Analysis of Gene Expression Data Derived from Bone Regeneration Specific cDNA Microarrays [J] . Jungnam Joo, Hongshik Ahn, Frank Lombardo, Journal of biopharmaceutical statistics . 2004,第3期

机译：骨再生特异性cDNA基因芯片的基因表达数据分析中的统计方法。
4. The Basic Statistical Methods Applied to Microarrays Genes Expression Analysis [C] . D. Komorowski, E. Tkacz International Special Topic Conference on Information Technology and Applications in Biomedicine . 2008

机译：应用于微阵列基因表达分析的基本统计方法
5. Statistical methods in the design and analysis of gene expression data from cDNA microarray experiments. [D] . Yang, Yee Hwa. 2002

机译：设计和分析cDNA微阵列实验的基因表达数据的统计方法。
6. Rank Difference Analysis of Microarrays (RDAM) a novel approach to statistical analysis of microarray expression profiling data [O] . Dietmar E Martin, Philippe Demougin, Michael N Hall, 2004

机译：微阵列的秩差分析（RDAM）一种微阵列表达谱数据统计分析的新方法
7. Estudos de expressão gênica utilizando-se microarrays: delineamento, análise, e aplicações na pesquisa zootécnica Microarray gene expression studies: experimental design, statistical data analysis, and applications in livestock research [O] . Guilherme Jordão de Magalhães Rosa, Leonardo Bernardes da Rocha, Luiz Roberto Furlan 2007

机译：微阵列基因表达研究：描绘，分析和在动物技术研究中的应用微阵列基因表达研究：实验设计，统计数据分析和家畜研究中的应用

Statistical design and the analysis of gene expression microarray data

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