Estimating the recombination parameter of a finite population model without selection

RICHARD R. HUDSON

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Estimating the recombination parameter of a finite population model without selection

机译：估计没有选择的有限人口模型的重组参数

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An estimator is proposed for the parameter C = 4Nc. where N is the population size and c is the recombination rate. The estimator is appropriate for use with sequence or restriction site data from random samples from within populations. Properties ofthe estimator are investigated for an infinite-sites neutral model using Monte Carlo simulations. The median and mode of the distribution of the estimator are close to the true value for all parameter values examined, but large data sets are required toobtain reliable estimates.

机译：针对参数C = 4Nc提出了一个估计器。其中N是种群数量，c是重组率。该估计器适合与来自人群中随机样本的序列或限制性位点数据一起使用。使用蒙特卡洛模拟对无限站点中性模型研究了估计器的属性。对于所检查的所有参数值，估计量的分布的中位数和众数均接近真实值，但是需要大量数据集才能获得可靠的估计值。

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《Genetical Research》 |2007年第6期|共6页
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RICHARD R. HUDSON;
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正文语种 eng
中图分类遗传学;
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1. Estimating the recombination parameter: a commentary on 'Estimating the recombination parameter of a finite population model without selection' by Richard R. Hudson [J] . Weir B S Genetical Research . 2007,第5a6期

机译：估计重组参数：Richard R. Hudson对“估计未经选择的有限总体模型的重组参数”的评论
2. Precision of recombination frequency estimates after random intermating with finite population sizes. [J] . Frisch M, Melchinger AE Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 2008,第1期

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3. Precision of Recombination Frequency Estimates After Random Intermating With Finite Population Sizes [J] . Albrecht E. Melchinger, Matthias Frisch Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 2008,第1期

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Estimating the recombination parameter of a finite population model without selection

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