...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of environmental science and health, Part A. Toxic/hazardous substances & environmental engineering >Dissolved organic matter and aluminum oxide nanoparticles synergistically cause cellular responses in freshwater microalgae
【24h】

Dissolved organic matter and aluminum oxide nanoparticles synergistically cause cellular responses in freshwater microalgae

机译：

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相关主题

摘要

This study investigated the impact of dissolved organic matters (DOM) on the ecological toxicity of aluminum oxide nanoparticles (Al(2)O(3)NPs) at a relatively low exposure concentration (1mg L-1). The unicellular green alga Scenedesmus obliquus was exposed to Al2O3NP suspensions in the presence of DOM (fulvic acid) at various concentrations (1, 10, and 40mg L-1). The results show that the presence of DOM elevated the growth inhibition toxicity of Al(2)O(3)NPs towards S. obliquus in a dose-dependent manner. Moreover, the combination of DOM at 40mg L-1 and Al(2)O(3)NPs resulted in a synergistic effect. The relative contribution of Al-ions released from Al(2)O(3)NPs to toxicity was lower than 5, indicating that the presence of the particles instead of the dissolved ions in the suspensions was the major toxicity sources, regardless of the presence of DOM. Furthermore, DOM at 10 and 40mg L-1 and Al(2)O(3)NPs synergistically induced the upregulation of intercellular reactive oxygen species levels and superoxide dismutase activities. Analysis of the plasma malondialdehyde concentrations and the observation of superficial structures of S. obliquus indicated that the mixtures of DOM and Al(2)O(3)NPs showed no significant effect on membrane lipid peroxidation damage. In addition, the presence of both DOM and Al(2)O(3)NPs contributed to an enhancement in both the mitochondrial membrane potential and the cell membrane permeability (CMP) in S. obliquus. In particular, Al(2)O(3)NPs in the presence of 10 and 40mg L-1 DOM caused a greater increase in CMP compared to Al(2)O(3)NPs and DOM alone treatments. In conclusion, these findings suggest that DOM at high concentrations and Al(2)O(3)NPs synergistically interrupted cell membrane functions and triggered subsequent growth inhibition toxicity.

著录项

获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号