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首页> 外文期刊>Family practice. >Can pharmacological treatment of behavioural disturbances in elderly patients with dementia lower the burden of their family caregiver?
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Can pharmacological treatment of behavioural disturbances in elderly patients with dementia lower the burden of their family caregiver?

机译：老年痴呆症患者的行为障碍的药物治疗可以减轻家庭护理人员的负担吗？

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Family caregivers of a community-dwelling demented relative experience significant burden in their caregiving role. In particular, behavioural disturbances are expected to be responsible for high caregiver distress and burden. Above, in approximately 80% of the cases, institutionalization of the demented patients with dementia occurs as a result of a burdened caregiver. Because of the impressive disruptive character of behavioural disturbances, most caregivers appeal for pharmacological intervention at a given moment, expecting instant suppression of the aberrant behaviour. Beside the antipsychotic drugs, the cholinesterase inhibitors are commonly used in the treatment of agitation, aggression, delusions, etc. Although in meta-analyses on the efficacy of both categories of drugs, only little evidence of their efficacy has been found and an important placebo effect has been reported that >90% of the demented elderly was treated at least once. The aim of this study was to investigate if pharmacological treatment of behavioural disturbances of the demented can lower the burden and the time spent in the family caregiver irrespective of their effect on the demented himself. A systematic literature search was performed by means of Medline, Embase, Cochrane DSR, Dare, CCTR and ACP Journal Club. Based on this review, pharmacological treatment of demented elderly seems to lower caregiver burden (mean difference 0.27) and the time caregivers spent (mean difference 41.65 minutes). Considering that family caregivers confronted with the troublesome behaviour of their demented relative will apply for pharmacological intervention, future research should particularly focus on the outcome measures of the caregivers' well-being.
机译：患有社区痴呆症的亲戚的家庭看护者在其看护角色上承受了沉重的负担。特别是，行为障碍预计会导致护理人员的高度痛苦和负担。以上，在大约80％的病例中，由于护理人员负担沉重，使患有痴呆症的痴呆患者住院治疗。由于行为障碍具有令人印象深刻的破坏性特征，因此大多数护理人员都希望在给定时刻进行药理干预，期望能够立即抑制异常行为。除抗精神病药外，胆碱酯酶抑制剂还常用于治疗躁动，攻击，妄想等。尽管在对这两类药物的疗效进行荟萃分析时，仍未发现其功效的证据，并且是重要的安慰剂据报道，超过90％的老年痴呆症患者至少接受了一次治疗。这项研究的目的是调查对痴呆症患者行为失常的药物治疗是否可以减轻负担和减少家庭看护人所花费的时间，而不论其对痴呆症患者自身的影响如何。通过Medline，Embase，Cochrane DSR，Dare，CCTR和ACP Journal Club进行了系统的文献检索。根据此评论，老年痴呆症患者的药物治疗似乎可以降低护理人员的负担（平均差异0.27）和护理人员所花费的时间（平均差异41.65分钟）。考虑到家庭护理人员面对其痴呆亲戚的麻烦行为会申请药理干预，因此未来的研究应特别关注护理人员幸福感的结果指标。

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