Mechanical ventilation is nowadays a well-developed, safe, and necessary strategy for acute respiratory distress syndrome patients to survive. However, the propagation of microbubbles in airway bifurcations during mechanical ventilation makes the existing lung injury more severe. In this paper, finite element and direct interface tracking techniques were utilized to simulate steady microbubble propagation in a twodimensional asymmetric bifurcating airway filled with a viscous fluid. Inertial effects were neglected, and the numerical solution of Stokes's equations was used to investigate how gravity and surface tension defined by a Bond (Bo) number and capillary (Ca) number influence the magnitudes of pressure gradients, shear stresses, and shear stress gradients on the bifurcating daughter airway wall. It is found that increasing Bo significantly influenced both the bubble shape and hydrodynamic stresses, where Bo ≥ 0.25 results in a significant increase in bubble elevation and pressure gradient in the upper daughter wall. Although for both Bo and Ca, the magnitude of the pressure gradient is always much larger in the upper daughter airway wall, Ca has a great role in amplifying the magnitude of the pressure gradient. In conclusion, both gravity and surface tension play a key role in the steady microbubble propagation and hydrodynamic stresses in the bifurcating airways.
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School of Natural and Applied Sciences, Department of Applied Mathematics, Northwestern Polytechnical University, Shaanxi, Xi'an 710072, People's Republic of China;
