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Approach to the child with coma: correspondence.

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In a recent paper "Approach to the Child with Coma", Sharma et al 1 have also included acidosis in the "Causes of coma in children" (Table 1, pg. 1280) and, later, on pg. 1280 and 1286 they have recommended "Acid base abnormalities should be corrected", without discussion of mechanisms causing coma in acidosis. For the readers of "Indian Journal of Pediatrics" it would be perhaps interesting to know the details, how acidosis (i. e., low blood pH = high concentration of hydrogen ions H~+) can cause coma, and, thus, why it is necessary to correct acidosis.

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