National surveillance of fungemia in Denmark (2004 to 2009).

Arendrup MC; Bruun B; Christensen JJFuursted KJohansen HKKjaeldgaard PKnudsen JDKristensen LMoller JNielsen LRosenvinge FSRoder BSchonheyder HCThomsen MKTruberg K

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National surveillance of fungemia in Denmark (2004 to 2009).

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A 6-year nationwide study of fungemia in Denmark was performed using data from an active fungemia surveillance program and from laboratory information systems in nonparticipating regions. A total of 2,820 episodes of fungemia were recorded. The incidence increased from 2004 to 2007 (7.7 to 9.6/100,000) and decreased slightly from 2008 to 2009 (8.7 to 8.6/100,000). The highest incidences were seen at the extremes of age (i.e., 11.3 and 37.1/100,000 for those 50 years of age. The species distribution varied significantly by both age and gender. Candida species accounted for 98 of the pathogens, and C. albicans was predominant, although the proportion decreased (64.4 to 53.2, P 4 mug/ml) occurred in C. albicans (7/1,183 0.6), C. dubliniensis (2/65 3.1), C. parapsilosis (5/83 6.0), and C. tropicalis (7/104 6.7). Overall, 70.8 of fungemia isolates were fully fluconazole susceptible, but the proportion decreased (79.7 to 68.9, P = 0.02). The study confirmed an incidence rate of fungemia in Denmark three times higher than those in other Nordic countries and identified marked differences related to age and gender. Decreased susceptibility to fluconazole was frequent and increasing.

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《Journal of Clinical Microbiology》 |2011年第1期|325-334|共10页
作者
Arendrup MC; Bruun B; Christensen JJFuursted KJohansen HKKjaeldgaard PKnudsen JDKristensen LMoller JNielsen LRosenvinge FSRoder BSchonheyder HCThomsen MKTruberg K;
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Unit of Mycology, Department of Microbiological Surveillance and Research 43/117, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen, Denmark.;

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正文语种英语
中图分类医学微生物学（病原细菌学、病原微生物学）;
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National surveillance of fungemia in Denmark (2004 to 2009).

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