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首页> 外文期刊>Maternal and child health journal >Parent-reported prevalence of autism spectrum disorders in US-born children: An assessment of changes within birth cohorts from the 2003 to the 2007 national survey of children's health
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Parent-reported prevalence of autism spectrum disorders in US-born children: An assessment of changes within birth cohorts from the 2003 to the 2007 national survey of children's health

机译：父母报告的美国出生的儿童自闭症谱系患病率：2003年至2007年全国儿童健康调查中出生队列变化的评估

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The prevalence of autism spectrum disorders (ASD) from the 2007 National Survey of Children's Health (NSCH) was twice the 2003 NSCH estimate for autism. From each NSCH, we selected children born in the US from 1990 to 2000. We estimated autism prevalence within each 1-year birth cohort to hold genetic and non-genetic prenatal factors constant. Prevalence differences across surveys thus reflect survey measurement changes and/or external identification effects. In 2003, parents were asked whether their child was ever diagnosed with autism. In 2007, parents were asked whether their child was ever diagnosed with an ASD and whether s/he currently had an ASD. For the 1997-2000 birth cohorts (children aged 3-6 years in 2003 and 7-10 years in 2007), relative increases between 2003 autism estimates and 2007 ASD estimates were 200-600 %. For the 1990-1996 birth cohorts (children aged 7-13 years in 2003) increases were lower; nonetheless, differences between 2003 estimates and 2007 "ever ASD" estimates were >100 % for 6 cohorts and differences between 2003 estimates and 2007 "current ASD" estimates were >80 % for 3 cohorts. The magnitude of most birth cohort-specific differences suggests continuing diagnosis of children in the community played a sizable role in the 2003-2007 ASD prevalence increase. While some increase was expected for 1997-2000 cohorts, because some children have later diagnoses coinciding with school entry, increases were also observed for children ages ≥7 years in 2003. Given past ASD subtype studies, the 2003 "autism" question might have missed a modest amount (≤33%) of ASDs other than autistic disorder.
机译：2007年全国儿童健康调查（NSCH）的自闭症谱系障碍（ASD）患病率是2003年NSCH对自闭症的估计数的两倍。从每个NSCH中，我们选择了1990年至2000年在美国出生的孩子。我们估计了每1岁出生队列中的自闭症患病率，以使遗传和非遗传的产前因子保持恒定。因此，各次调查的患病率差异反映了调查的测量变化和/或外部识别效果。 2003年，父母被问及自己的孩子是否曾经被诊断出患有自闭症。在2007年，父母被问及他们的孩子是否曾经被诊断出患有自闭症，以及他/她目前是否患有自闭症。对于1997-2000年出生队列（2003年为3-6岁，2007年为7-10岁），2003年自闭症估计数与2007年ASD估计数之间的相对增长为200-600％。对于1990-1996年的出生队列（2003年年龄在7-13岁之间的儿童）而言，增长率较低;但是，对于6个队列，2003年估计值与2007年“以往ASD”估计值之间的差异> 100％，对于3个队列，2003年估计与2007年“当前ASD”估计值之间的差异大于80％。大多数特定于出生队列的差异的幅度表明，社区儿童的持续诊断在2003-2007年ASD患病率上升中起着重要作用。尽管预计1997-2000年的队列会有所增加，因为一些孩子后来诊断出与入学时间相吻合，但2003年≥7岁的孩子也有所增加。考虑到过去的ASD亚型研究，2003年的“自闭症”问题可能会遗漏除自闭症外，适度（≤33％）的自闭症患者。

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