Imperative of continual support by the European Community for future advances in paediatric oncology in Europe: meeting report of the EC-funded science-communication project DIRECT 'Overcoming Cancer with Research'

G. Tailen; M. Dworzak; h. Gadner; G. Masera; M. Schrappe; A. Biondi; G. Vassal; R. Pieters; J. Jazbec; B. Morland; U. Creutzig

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Imperative of continual support by the European Community for future advances in paediatric oncology in Europe: meeting report of the EC-funded science-communication project DIRECT 'Overcoming Cancer with Research'

机译：迫切需要欧洲共同体继续支持欧洲儿科肿瘤学的未来发展：欧洲共同体资助的科学传播项目直接报告“通过研究克服癌症”的会议报告

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Background/Purpose: Remarkable advances in paediatric cancer research and treatment were achieved during the last decades: In industrialised nations, overall cure rates were raised from below 20% to over 75% during the last forty years. Randomised investigator-driven clinical trials have been the backbone of this progress so far. The EU Clinical Trial Directive was introduced to improve the quality and safety of drug development; however, it has created considerable administrative "extra" workload as well as financial constraints for trials aiming at cancer treatment optimisation in children. It failed to provide harmonisation for clinical trials throughout Europe because translation into national law was highly divergent. To address the resulting challenges for future advances in European paediatric oncology including the promotion of new drug development, improved communication between all stakeholders is warranted.

机译：背景/目的：在过去的几十年中，儿科癌症研究和治疗取得了显着进展：在工业化国家中，过去40年中，总治愈率从20％以下提高到75％以上。迄今为止，由研究人员驱动的随机临床试验一直是这一进展的基础。引入了欧盟临床试验指令以提高药物开发的质量和安全性;然而，它为旨在优化儿童癌症治疗的试验创造了可观的行政“额外”工作量以及财务限制。它未能为整个欧洲的临床试验提供统一性，因为翻译成国家法律的分歧很大。为了应对欧洲儿科肿瘤学未来进展（包括促进新药开发）带来的挑战，必须保证所有利益相关者之间的交流更加畅通。

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《Memo - Magazine of European medical oncology》 |2009年第4期|共12页
作者
G. Tailen; M. Dworzak; h. Gadner; G. Masera; M. Schrappe; A. Biondi; G. Vassal; R. Pieters; J. Jazbec; B. Morland; U. Creutzig;
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正文语种 eng
中图分类肿瘤学;
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1. Imperative of continual support by the European Community for future advances in paediatric oncology in Europe: meeting report of the EC-funded science-communication project DIRECT “Overcoming Cancer with Research” [J] . G. Tallen, M. Dworzak, H. Gadner, memo - Magazine of European Medical Oncology . 2009,第4期

机译：迫切需要欧洲共同体继续支持欧洲儿科肿瘤学的未来发展：欧洲共同体资助的科学传播项目直接报告“通过研究克服癌症”的会议报告
2. More and better cure for an orphan: priorities for future paediatric cancer research in Europe – Meeting report of the EC-funded science-communication project DIRECT “Overcoming Cancer with Research” [J] . G. Tallen, M. Dworzak, H. Gadner, memo - Magazine of European Medical Oncology . 2009,第4期

机译：为孤儿提供更多更好的治疗方法：欧洲未来儿科癌症研究的重点– EC资助的科学传播项目DIRECT“通过研究克服癌症”的会议报告
3. More and better cure for an orphan: priorities for future paediatric cancer research in Europe - Meeting report of the EC-funded science-communication project DIRECT "Overcoming Cancer with Research" [J] . G. Taller, M. Dworzak, H. Gadner, Memo - Magazine of European medical oncology . 2009,第4期

机译：为孤儿提供更多更好的治疗方法：欧洲未来儿科癌症研究的重点-EC资助的科学传播项目DIRECT“通过研究克服癌症”的会议报告
4. Architecture for an Advanced Biomedical Collaboration Domain for the European Paediatric Cancer Research Community (ABCD-4-E) [C] . Michael NITZLNADER, Markus FALGENHAUER, Christian GOSSY, Scientific eHealth Conference. . 2015

机译：欧洲儿科癌症研究界的高级生物医学协作领域的架构（ABCD-4-E）
5. Adolescents and young adults (AYA) with cancer: a position paper from the AYA Working Group of the European Society for Medical Oncology (ESMO) and the European Society for Paediatric Oncology (SIOPE) [O] . A. Ferrari, D. Stark, F.A. Peccatori, 2021

机译：患有癌症的青少年和年轻人（AYA）：来自欧洲医学肿瘤学会（ESMO）和欧洲儿科肿瘤学会（SIOPE）的AYA工作组的立场文件
6. Report drawn up on behalf of the Committee on Energy and Research on I. the communication from the Commission of the European Communities to the Council on evaluation of the Community demonstration programmes in the energy sector, II. the proposals from the Commission of the European Communities to the Council for -a Regulation (EEC) on the granting of financial support for a demonstration projects relating to the exploitation of alternative energy sources, energy-saving and the substitution of hudrocarbons sic, - a Regulation (EEC) on the granting of financial support for pilot industrial projects and demonstration projects relating to the liquefaction and gasification of solid fuels, Working Documents 1982-1983, Document 1-670/82, 11 October 1982 [O] . Normanton T. 1982

机译：代表能源和研究委员会编写的报告I.欧洲共同体委员会向理事会提交的关于评估能源部门共同体示范项目的信息，II。欧洲共同体委员会向管理委员会提出的关于为与替代能源的开发，节能和替代碳氢化合物的示范项目提供财政支持的建议（欧洲经济共同体），sic， - 关于为与固体燃料的液化和气化有关的试点工业项目和示范项目提供资金支持的条例（EEC），工作文件1982-1983，文件1-670 / 82，1982年10月11日
7. (European Accelerator Conference, Rome, Italy, International Committee for Future Accelerators Annual Meeting and Workshop, Capri Island, June 7--18, 1988): Foreign Trip Report. [R] . Palmer, R. B. 1988

机译：（欧洲加速器会议，意大利罗马，国际未来加速器年会和研讨会，卡普里岛，1988年6月7日至18日）：外国旅行报告。

Imperative of continual support by the European Community for future advances in paediatric oncology in Europe: meeting report of the EC-funded science-communication project DIRECT 'Overcoming Cancer with Research'

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