...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>cell and tissue research >An ultrastructural examination of the action of vinblastine on microtubules, neurofilaments and muscle filamentsin vitro
【24h】

An ultrastructural examination of the action of vinblastine on microtubules, neurofilaments and muscle filamentsin vitro

机译：

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In vitroincubation of autonomic nerves with vinblastine sulphate (1×10-4M) caused a disappearance of microtubules within 15 min; during the following 15 min paracrystalline arrays appeared within the axons. An increase in the abundance of microfilaments was also observed, but these did not appear to arise from disaggregated microtubules since the increase in microfilament numbers was noted at an incubation time when crystal formation was extensive. Pretreatment of autonomic nerves with colchicine (2.5×10-4M) caused a reduction of approximately 80 in the numbers of microtubules, but did not prevent the formation of crystals on subsequent exposure to vinblastine. No ultrastructural changes were observed in myofilaments on incubation with vinblastin

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号