Gr(i)p the ER to Stress Out Melanoma

Xu Wanping; Neckers Len

首页> 外文期刊>Cancer Cell >Gr(i)p the ER to Stress Out Melanoma

【24h】

Gr(i)p the ER to Stress Out Melanoma

机译：Gr（i）p ER缓解黑色素瘤

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Because of their elevated steady-state stress level, cancer cells are particularly sensitive to perturbation of mechanisms regulating protein homeostasis. In this issue, Cerezo and colleagues show that pharmacologic modulation of GRP78, master regulator of the unfolded protein response in the endoplasmic reticulum, can be exploited for cancer treatment.

机译：由于其升高的稳态压力水平，癌细胞对调节蛋白质稳态的机制特别敏感。 Cerezo及其同事在本期杂志中表明，可以利用GRP78（内质网中未折叠的蛋白质反应的主要调节剂）的药理调节作用来治疗癌症。

著录项

来源
《Cancer Cell》 |2016年第6期|共3页
作者
Xu Wanping; Neckers Len;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词

相似文献

外文文献
中文文献
专利

1. Static recrystallization and grain growth during annealing of an extruded Mg-Zn-Zr-Er magnesium alloy [J] . Jing Zhang, Weiguo Li, Zhengxiao Guo 镁合金学报（英文） . 2013,第001期
2. Loss of a Clueless-dGRASP complex results in ER stress and blocks Integrin exit from the perinuclear endoplasmic reticulum in Drosophila larval muscle Loss of a Clueless-dGRASP complex results in ER stress and blocks Integrin exit from the perinuclear endoplasmic reticulum in Drosophila larval muscle Loss of a Clueless-dGRASP complex results in ER stress and blocks Integrin exit from the perinuclear endoplasmic reticulum in Drosophila larval muscle [J] . Zong-Heng Wang, Erika R. Geisbrecht, Catherine Rabouille Biology Open . 2015,第5期

机译：无味-dGRASP复合物的丧失导致果蝇幼虫肌肉的内质网应激，并阻止整合素从果蝇幼虫肌肉的内周网状结构中丢失。无线索-dGRASP复合物导致内质网应激，并阻止果蝇幼虫肌肉中整联蛋白从核周内质网排出
3. Plumbagin inhibits melanoma cell growth and tumorigenicity by inducing ER Stress and DDR signaling [J] . Afaq F., Sharma P., McClees S. F., The Journal of investigative dermatology. . 2017,第5期

机译：通过诱导ER应力和DDR信号传导，肠果抑制黑素瘤细胞生长和致瘤性
4. Clinical and Pathological Significance of ER Stress Marker (BiP/GRP78 and PERK) Expression in Malignant Melanoma [J] . Akira Shimizu, Kyoichi Kaira, Masahito Yasuda, Pathology oncology research: POR . 2017,第1期

机译：恶性黑色素瘤中ER应激标志物（BiP / GRP78和PERK）表达的临床和病理意义
5. ER stress-induced binding of Group VIA PLA_(2)(iPLA_(2)beta) to calnexinidentified by mass spectrometric characterization of the iPLA_(2)beta interactome [C] . Haowei Song, Henry Rohrs, Jack Ladenson, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：通过PLA_（2）（IPLA_（2）β）来应力诱导基团的结合，以通过质谱表征IPLA_（2）β互联蛋白酶的质谱表征
6. ER Stress Sensor IRE1α and Its Implications in Progression of Hepatocellular Carcinoma [D] . Oak, Amrita . 2019

机译：ER应激传感器IRE1α及其在肝细胞癌进展中的影响
7. Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death [O] . Tharcisio Citrangulo Tortelli Junior, Lyris Martins Franco de Godoy, Gustavo Antonio de Souza, 2017

机译：禁止素的积聚是对不同压力刺激的常见细胞反应并保护黑素瘤细胞免受内质网应激和化疗诱导的细胞死亡
8. Shrimp miR-965 induced the human melanoma stem-like cell apoptosis and inhibited their stemness by disrupting the MCL-1-ER stress-XBP1 feedback loop in a cross-species manner [O] . Wenlin Wu, Chenxi Xu, Xiaobo Zhang, 2020

机译：虾MiR-965诱导人黑色素瘤干细胞凋亡，并通过以横谱仪破坏MCL-1-ER应力-XBP1反馈环来抑制它们的茎
9. Siah1/2 Ubiquitin Ligases in ER Stress Signaling in Melanoma. [R] . Ronai, Z. 2016

机译：siah1 / 2泛素连接酶在黑色素瘤的ER应激信号。

Gr(i)p the ER to Stress Out Melanoma

摘要

著录项

相似文献

相关主题

期刊订阅