Aqueous phase synthesis of substituted imidazo1,2-apyridine in the presence of Î²-cyclodextrin

Vijay V. Kumbhar; Shankar P. Hangirgekar; NavanB. Wadwale

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Aqueous phase synthesis of substituted imidazo1,2-apyridine in the presence of Î²-cyclodextrin

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A simple and practical procedure for aqueous phase reaction of various alpha;-tosyloxy ketones with 2- amino pyridine and their derivatives in the presence of beta;-Cyclodextrin has been developed to furnish bridgehead azaheterocycles 3a-h amp; 4a-d in good to excellent yields.

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《Der Pharma Chemica》 |2013年第5期|274-279|共6页
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Vijay V. Kumbhar; Shankar P. Hangirgekar; NavanB. Wadwale;
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2. Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo(1,2-a)pyridines and 5,6,7,8-tetrahydro-imidazo(1,2-a)pyridines. [J] . Ismail MA, Arafa RK, Wenzler TBrun RTanious FAWilson WDBoykin DW Bioorganic and medicinal chemistry . 2008,第2期

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4. INTRAOCULAR PRESSURE LOWERING EFFECT OF IMIDAZO1, 2-a BENZIMIDAZOLE AND PYRIMIDO1, 2-aBENZIMIDAZOLE COMPOUNDS IN OCULAR NORMOTENSIVE AND HYPERTENSIVE RATS [O] . Igor Iezhitsa, Adrian J Marcus, Renu Agarwal, 2018

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Aqueous phase synthesis of substituted imidazo1,2-apyridine in the presence of Î²-cyclodextrin

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