Disseminated Herpes Simplex Infection Presenting as Acute Supraglottitis in an Adult

Bowers Eve M. R.; Esianor Brandon I.; Kimura KyleLewis James S.Topf Michael C.

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Disseminated Herpes Simplex Infection Presenting as Acute Supraglottitis in an Adult

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Supraglottitis is a life-threatening, predominantly bacterial disease that is rarely caused by viral etiologies. Herpes Simplex Virus (HSV) supraglottitis has been infrequently reported, but its presentation can mimic that of bacterial supraglottitis or pharyngitis which may lead to delayed diagnosis and increased morbidity. We present a case of supraglottitis in an immunocompetent man initially thought to have bacterial epiglottitis. After receiving a tracheostomy due to impending airway compromise and failing to improve on antibiotic therapy, biopsy of the upper airway tissue revealed infection with HSV type 2. The patient improved after multiple weeks of systemic antivirals. HSV supraglottitis remains an unusual but important diagnostic consideration in patients with dysphonia, dysphagia, ulcerative supraglottal lesions, and acute supraglottic inflammation unresponsive to antibiotics.

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《head & neck pathology》 |2021年第3期|1074-1081|共8页
作者
Bowers Eve M. R.; Esianor Brandon I.; Kimura KyleLewis James S.Topf Michael C.;
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作者单位

Univ Pittsburgh;

Vanderbilt Univ;

Vanderbilt Univ;

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原文格式 PDF
正文语种英语
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关键词
Airway obstruction; Etiology; Diagnosis; Differential; Supraglottitis; Herpes Simplex; Complications; Humans; Laryngitis; Male; Tracheitis; ACUTE EPIGLOTTITIS; VIRAL SUPRAGLOTTITIS; AIRWAY-OBSTRUCTION; LARYNGEAL HERPES; VIRUS TYPE-1; LARYNGITIS; HEPATITIS;

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2. Disseminated herpes simplex virus infection with hepatitis in an adult renal transplant recipient [J] . DPWalker, MLongson, WLawlerNPMallickJSDaviesRWGJohnson journal of clinical pathology . 1981,第9期

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3. Low Risk of Herpes Simplex Virus Infections in Neonates Exposed to the Virus at the Time of Vaginal Delivery to Mothers with Recurrent Genital Herpes Simplex Virus Infections [J] . C. Prober, W. Sullender, L. YasukawaD. AuA. YeagerA. Arvin obstetric anesthesia digest . 1987,第2期

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Disseminated Herpes Simplex Infection Presenting as Acute Supraglottitis in an Adult

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