Synaptophysin Positive Glomus Tumor of Trachea Simulating Typical Carcinoid: A Potential trap

Kamboj Meenakshi; Durga Garima; Pasricha SunilDarlong L. M.Jajodia AnkushGupta GuruduttSharma AnilaKoyyala Venkata Pradeep BabuMehta Anurag

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Synaptophysin Positive Glomus Tumor of Trachea Simulating Typical Carcinoid: A Potential trap

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Glomus tumors (GTs) are uncommon benign tumors, accounting for <2 of all soft tissue tumors and usually occur within the dermis or subcutis of distal extremities. Primary tracheal GT is rare, and to date less than 40 tracheal GTs have been reported. Tracheal GT usually present as a polypoidal mass. They express smooth muscle markers, and are negative for cytokeratin (CK) and neuroendocrine markers on immunohistochemistry (IHC). We here report a case of tracheal GT showing diffuse strong aberrant immunoexpression for synaptophysin, initially construed as carcinoid. Focal synaptophysin expression has been described in few gastric GTs, and a nasal GT. Diligent histomorphological examination and careful selection of IHC panel helps in clinching the diagnosis. Complete resection is the standard treatment of modality.

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《head & neck pathology》 |2021年第3期|994-998|共5页
作者
Kamboj Meenakshi; Durga Garima; Pasricha SunilDarlong L. M.Jajodia AnkushGupta GuruduttSharma AnilaKoyyala Venkata Pradeep BabuMehta Anurag;
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作者单位

Rajiv Gandhi Canc Inst & Res Ctr;

Rajiv Gandhi Canc Inst & Res Ctr;

Rajiv Gandhi Canc Inst & Res CtrRajiv Gandhi Canc Inst & Res Ctr;

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原文格式 PDF
正文语种英语
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Glomus tumor; Synaptophysin; Trachea;

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Synaptophysin Positive Glomus Tumor of Trachea Simulating Typical Carcinoid: A Potential trap

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