Organoid based personalized medicine: from bench to bedside

Li Y.; Tang P.; Cai S.Peng J.Hua G.

首页> 外文期刊>cell regeneration >Organoid based personalized medicine: from bench to bedside

【24h】

Organoid based personalized medicine: from bench to bedside

机译：

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

© 2020, The Author(s).Three-dimensional cultured organoids have become a powerful in vitro research tool that preserves genetic, phenotypic and behavioral trait of in vivo organs, which can be established from both pluripotent stem cells and adult stem cells. Organoids derived from adult stem cells can be established directly from diseased epithelium and matched normal tissues, and organoids can also be genetically manipulated by CRISPR-Cas9 technology. Applications of organoids in basic research involve the modeling of human development and diseases, including genetic, infectious and malignant diseases. Importantly, accumulating evidence suggests that biobanks of patient-derived organoids for many cancers and cystic fibrosis have great value for drug development and personalized medicine. In addition, organoids hold promise for regenerative medicine. In the present review, we discuss the applications of organoids in the basic and translational research.

著录项

来源
《cell regeneration》 |2020年第1期|共页
作者
Li Y.; Tang P.; Cai S.Peng J.Hua G.;
展开▼
作者单位

Department of Colorectal Surgery Fudan University Shanghai Cancer Center;

Department of Oncology Shanghai Medical College Fudan University;

Institute of Radiation Medicine Fudan University Shanghai Cancer CenterCancer institute Fudan University Shanghai Cancer Center;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类
关键词
Biobanks; Disease modeling; Organoids; Personalized medicine; Stem cells;

相似文献

外文文献
中文文献
专利

1. Sequence-based diagnostics and precision medicine in bacterial and viral infections: from bench to bedside [J] . JonathanPham, LingHui DavidSu, Kimberly EHansonCatherine AHogan Current opinion in infectious diseases . 2023,第4期

机译：Sequence-based diagnostics and precision medicine in bacterial and viral infections: from bench to bedside
2. AGuIX ? from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine [J] . FRANCOIS LUX, VU LONG TRAN, ELOISE THOMASSANDRINE DUFORTFABIEN ROSSETTIMATTEO MARTINICHARLES TRUILLETRISTAN DOUSSINEAU British Journal of Radiology . 2019,第1093期

机译：AGuIX ? from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine
3. Organoids of liver diseases: From bench to bedside [J] . Li-Jun Wu, Zi-Yan Chen, Yi WangJun-Gang ZhaoXiao-Zai XieGang Chen world journal of gastroenterology . 2019,第16期

机译：Organoids of liver diseases: From bench to bedside
4. Personalized PageRank の高速計算手法 [C] . 藤原靖宏情報処理学会全国大会 . 2016

机译：Personalized PageRank の高速计算手法
5. 信息不对称下，“中药材全产业链服务商”模式对中药材价格的影响研究 =Pricing and Information Asymmetry in the Chinese Herbal Medicine Markets - A Study of the Mode of "Chinese Herbal Medicine Industry Chain Service Provider" [D] . Yin, Xiaowei. 2019

机译：信息不对称下，“中药材全产业链服务商”模式对中药材价格的影响研究 =Pricing and Information Asymmetry in the Chinese Herbal Medicine Markets - A Study of the Mode of "Chinese Herbal Medicine Industry Chain Service Provider"
6. Building the Partners HealthCare Biobank at Partners Personalized Medicine: Informed Consent Return of Research Results Recruitment Lessons and Operational Considerations [O] . Elizabeth W. Karlson, Natalie T. Boutin, Alison G. Hoffnagle, 2016

机译：在Partners Personalized Medicine上建立Partners HealthCare生物库：知情同意研究结果返回招聘经验教训和操作注意事项
7. Transtornos mentais comuns e o uso de práticas de medicina complementar e alternativa: estudo de base populacional Commom mental disorders and the use of complementary and alternative medicine: population-based survey [O] . João Felício Rodrigues-Neto, Maria Fernanda Santos Figueiredo, Anderson Antônio de Silveira Faria, 2008

机译：Transtornos mentais comuns e o usodepráticasdemedicina alternar e alternativa：estudo de base popralcional Commom psych disorder and the complementary with complementary and alternative medicine：population-based survey
8. Metodi Microbiologici Tradizionali e metodi molecolari per l'analisi degli integratori alimentari a base di o con probiotici per ujso umano (Microbiological and Molecular Methods for Analysis of Probiotic Based Food Supplements for Human Consumption). [R] . Aureli, P., Fiore, A., Scalfaro, C., 2008

机译：metodi microbiologici Tradizionali e metodi moleculeolari per l'analisi degli integratori alimentari a base di o con probiotici per ujso umano（microbiological and molecular methods for analysis of probiotic Based Food supplements for Human Consumption）。

Organoid based personalized medicine: from bench to bedside

摘要

著录项

相似文献

相关主题

期刊订阅