A new crystal form and anti#173;microbial activity of (E)-1-3-(2-hy#173;droxy#173;benzyl#173;idene#173;amino)#173;phen#173;ylethanone

Moussa Slimane N.; Bouhidel Z.; Cherouana A.

首页> 外文期刊>Acta Crystallographica Section E: Crystallographic Communications >A new crystal form and anti#173;microbial activity of (E)-1-3-(2-hy#173;droxy#173;benzyl#173;idene#173;amino)#173;phen#173;ylethanone

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A new crystal form and anti#173;microbial activity of (E)-1-3-(2-hy#173;droxy#173;benzyl#173;idene#173;amino)#173;phen#173;ylethanone

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The title Schiff base compound, C15H13NO2, crystallizes in a new crystal form in the space group P212121, which is different from the monoclinic P21/n space group reported previously De et al. (2009). Indian J. Chem. Sect. B, 48, 595#8211;598. An intra#173;molecular O#8212;H#8943;N hydrogen bond occurs between the hy#173;droxy and azomethine moieties. In the crystal, mol#173;ecules are linked by weak C#8212;H#8943;O hydrogen bonds into supra#173;molecular chains propagating along the b-axis direction with a C(8) graph-set motif. The contribution of these two contacts in Hirshfeld surface area are around 19 and 21, respectively. The title compound was screened for its anti#173;bacterial activity against two gram-negative (Escherichia coli and Salmonella typhimurium) and one gram-positive (Staphyloccus aureus) bacteria. The results of this study reveal that this Schiff base shows good activity against only one bacterium, i.e. Salmonella typhimurium.

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《Acta Crystallographica Section E: Crystallographic Communications》 |2018年第7期|884-888|共5页
作者
Moussa Slimane N.; Bouhidel Z.; Cherouana A.;
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作者单位

Unit de Recherche de Chimie de l'Environnement et Molculaire Structurale (URCHEMS), Dpartement de Chimie, Universit des freres Mentouri-Constantine 1, 25000 Constantine, Algeria;

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CRYSTAL STRUCTURE; SCHIFF BASE; NEW CRYSTAL FORM; HIRSHFELD SURFACES; ANTIMICROBIAL ACTIVITY;

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A new crystal form and anti#173;microbial activity of (E)-1-3-(2-hy#173;droxy#173;benzyl#173;idene#173;amino)#173;phen#173;ylethanone

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