Tumor-induced hypercalcemia

Hopfer O.; Gawliczek A.; Kiehl M. G.

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Tumor-induced hypercalcemia

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abstract_textpHypercalcemia is in many cases a symptom of advanced stage malignant diseases due to increased resorption and reduced secretion. A slightly increased hypercalcemia is mostly asymptomatic but high calcium levels are associated with neurological, gastrointestinal, cardiac and renal symptoms. Important diagnostic tools are the determination of serum albumin and ionized calcium levels. Therapeutic intervention depends on the clinical symptoms as well as calcium levels. Furthermore, increase over time and duration of hypercalcemia has to be taken into account. The principles of treatment are sufficient fluid replacement and maintaining adequate diuresis. In addition, calcitonin, bisphosphonates and steroids are effective and widely used to decrease plasma calcium levels./p/abstract_text

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《Der Internist》 |2013年第9期|1043-+|共6页
作者
Hopfer O.; Gawliczek A.; Kiehl M. G.;
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Klinikum Frankfurt Oder GmbH, Med Klin Schwerpunkt Hamatol Internist Onkol & Pu, D-15236 Frankfurt, Oder, Germany;

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正文语种英语
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Neoplasms; Serum albumin; Diuresis; Calcitonin; Bisphosphonates; CANCER-ASSOCIATED HYPERCALCEMIA; HORMONE-RELATED PROTEIN; INTRAVENOUS BISPHOSPHONATES; MULTIPLE-MYELOMA; MALIGNANCY; BONE; MANAGEMENT; LYMPHOMA; PAMIDRONATE; MECHANISMS;

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Tumor-induced hypercalcemia

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