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The world within

机译:内心世界

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摘要

The microbial communities that colonize living organisms are collectively referred to as the 'microbiota'. These resident commensals are well adapted to the ecological conditions of their host and constitute a complex ecosystem in which host-microbe, environment-microbe and microbe-microbe interactions dictate the composition and dynamics of the community. As with every ecosystem, commensal species occupy a niche, are evolutionarily adapted and continuously selected by the environmental pressures in the niche, and compete with other species for niche resources. In mammals, the gut microbiota has coevolved to provide essential functions for host physiological processes, such as the acquisition of nutrients, the development and maturation of the immune system and enhancement of the intestinal barrier. In this issue of Nature Immunology, we provide a series of specially commissioned articles to discuss recent advances on the understanding of the complex relationship between the microbiota and the host immune system (http://www.nature. comi/fo cus/microbiota).
机译:定居在生物体中的微生物群落统称为“微生物群”。这些居民奖章非常适合其宿主的生态条件,并构成了一个复杂的生态系统,其中宿主-微生物,环境-微生物和微生物-微生物的相互作用决定了社区的组成和动态。与每个生态系统一样,共生物种占据着生态位,在生态位中受到环境压力的影响不断地适应和选择,并与其他物种争夺生态位资源。在哺乳动物中,肠道菌群已经进化为宿主的生理过程提供了必要的功能,例如营养的获取,免疫系统的发育和成熟以及肠道屏障的增强。在本期《自然免疫学》中,我们提供了一系列特别委托的文章,以讨论有关微生物群与宿主免疫系统之间复杂关系的理解的最新进展(http://www.nature。com / ni / fo cus /微生物群)。

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