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首页> 外文期刊>Global journal of medicine and public health. >Spirulina as a main source of tryptophan for mental illness: Improving level of serotonin through tryptophan supplementation
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Spirulina as a main source of tryptophan for mental illness: Improving level of serotonin through tryptophan supplementation

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Spirulina be an excellent source of proteins, vitamins, lipids, minerals,carbohydrates, nucleic acids, enzymes and pigments. It is useful in humannutrition, due to the high quality and quantity of its protein (60‐70 of its dryweight). Tryptophan, the natural amino acid precursor in 5‐HT biosynthesis,increases serotonin synthesis in the brain. serotonin synthesis mostly willdepend on numerous factors including the free plasma tryptophan levels, theplasma levels of tryptophan relative to the other large neutral amino acids, theactivity of the system that transports the large neutral amino acids into brain,the gene expression of tryptophan hydroxylase, degradation of tryptophanhydroxylase, compartmentalization of tryptophan and tryptophan hydroxylasein brain cells. The best ways of mental health recovery and prevention is nutritional therapy throughsupplementing specific nutrients like tryptophan. Such supplementation can help for controlling andpreventing mental illness like depression, bipolar disorder, schizophrenia, eating disorders and anxietydisorders, attention deficit disorder/attention deficit hyperactivity disorder (ADD/ADHD), autism, andsubstance use disorder.

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